A fifth U.S. Air Force F-22 fighter has crashed. This occurred on November 15th in Florida during a training flight. The pilot safely ejected. Two of the five crash losses were during testing and in three of the crashes the pilot survived. The first crash occurred in 1992, destroying the first YF-22 prototype. The first production F-22 lost was in 2004. That was followed in 2009, by the loss of an F-22 during a test flight. Another was lost in 2010, during a training flight.
The 187th, and last, F-22 fighter was completed on December 13th 2011. This last aircraft was sent to a squadron in Alaska which lost one in an accident in 2010. The manufacturer is not going to scrap or sell off the tools and equipment used to produce the F-22 but will store the stuff for a while in the hope that production may resume eventually. There were also eight development prototypes built, for a total of 195 F-22s. With the five crashes, that leaves 190, but most of the remaining prototype aircraft are out of service. Currently 182 production aircraft are in service with 15 squadrons (three of them for training).
With the recent accident, the F-22 accident rate is a little over 6 per 100,000 hours. Note that the accident rate refers to any incident that costs more than a million dollars to repair, not just total loss of aircraft. F-15s and F-16s have an accident rate of 3-4 per 100,000 flight hours. India, using mostly Russian aircraft, has an accident rate of 6-7 per 100,000 hours flown (compared to 4-5 for all NATO air forces.) The Indian rate had been over ten for many years, and it is still that high, and often higher, with other nations (including Russia and China), that use Russian aircraft designs. The B-52 has the lowest accident rate (less than 1.5 per 100,000 flying hours) of all American heavy bombers. The B-1s rate is 3.48. Compared to the supersonic B-1 and high-tech B-2, the B-52 is a flying truck. Thus the B-52, despite its age, was the cheapest, safest, and most reliable way to deliver smart bombs.
New aircraft always have higher accident rates, which is how many hidden (from the design engineers and test pilots) flaws and technical problems are discovered. The F-22 is expected to eventually have an accident rate of 2-3 per 100,000 flight hours.
Combat aircraft are becoming more reliable, even as they become more complex. For example, in the early 1950s, the F-89 fighter had 383 accidents per 100,000 flying hours. A decade later the rate was in the 20s for a new generation of aircraft. At the time the F-4, which served into the 1990s, had a rate of under 5 per 100,000 hours. Combat aircraft have gotten more reliable and easier to maintain, despite growing complexity, for the same reason automobiles have. Better engineering, and more sensors built into the equipment, makes it easier for the user and maintenance personnel to detect potential problems. Aircraft used the computerized maintenance systems, currently common on new aircraft, long before automobiles got them. Unless you have a much older car that still runs, or a real good memory, you don't notice the enormous increase in automobile reliability. But older pilots remember because such changes are a matter of life and death if you make your living driving an aircraft. And commanders know that safer aircraft give them more aircraft to use in combat and more aircraft that can survive combat damage and keep fighting.