An RPG called Rifts, created by Kevin Siembieda addresses the animal man super soldier scenario.  The empire of man in North America called the Coalition experimented with all sorts of animal hybrids and concluded only the dog species was reliable, as they are naturally loyal pack animal.  Other hybrid species ended up running off at the first chance of escape joining mutant gangs.  The real story to such a scenario is the social status of these beasts, are they seen as equals to there human masters, property of the government or worshiped as heroes and saviors of mankind.  In Rifts they are treated as a slave race created by man for man to do dangerous jobs where a human might die, thus send in the dog.  Another hybrid story took the shape of a graphic novel that exploded onto main stream with cartoons, toys, movies, lunchboxes? Teenage Mutant Ninja Turtles deplicts an ?accidental? mutation which left these creatures living in the sewers only to leave to save the earth.  Even if hybrids were created tomorrow there rights would be limited at best as humans have a natural tendency to view anything nonhuman or less human as less intelligent or even instilled without a soul.  I encourage you Miles to push your idea to limit and create a novel on this subject their can never be too many books and your spin can only add to the genre.