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Don't Do This At Home Kids, Please

NUCLEAR, BIOLOGICAL AND CHEMICAL WEAPONS

August 6, 2009: There's been an outbreak of pneumonic plague in China, with several dozen cases, and a few deaths. This is the same disease that killed over a quarter of Europe's population in the 14th century. Before that, it did similar damage across Eurasia, all the way to China and Southeast Asia. Plague (usually the bubonic version, caught from insect bites, rather than the more rare pneumonic form, spread by sneezing) is no longer the big killer it once was. That's mainly because of better public health, and particularly because of the development of antibiotics in the 1940s. Plague, unlike most mass killers, is not caused by a virus, but by a bacteria.

But at the same time British researchers were developing penicillin, the Japanese Army, in the form of Unit 731 in northern China, was trying to turn plague into a weapon. This proved impossible to do. The Japanese dropped bombs filled with fleas (the normal carriers of Bubonic Plague) on Chinese villages, and the result was often no plague cases at all.

Plague still survives, in animal populations, all over the world. But in the last century, there have been only about 100-150 cases a year, and only about ten percent of them resulted in deaths. The last big outbreak in the United States was in Los Angeles in 1924, when there were 38 cases, most of them fatal. There are still periodic outbreaks in the American West, where people encounter plague infected animals in remote areas. But medical personnel in those areas know the symptoms, and quickly administer antibiotics. Thus there are few deaths.

The recent deaths in China make for good headlines, but apparently efforts to design (via genetic engineering) a "Super Pneumonic Plague" that is resistant to antibiotics, has not succeeded. There are much better super-germ opportunities with viruses. But the main problem with any of these biological weapons is that they kill indiscriminately. Turn it loose, and your own population is at risk.

A more serious problem is the increasing ease with which scientists can do genetic engineering on viruses and bacteria. It's likely that eventually, a super (as in killer) germ will be created and released by accident, because some bright (but doomed) teenager couldn't resist messing about with mom's genetic engineering gear.

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Bob Cortez       8/6/2009 6:50:15 AM
Read Preston: making superbug is open source. 
 
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Wicked Chinchilla       8/6/2009 8:24:01 AM
"This proved impossible to do."  I would have to add by the Japanese to this sentence.  Plague has been weaponized by the U.S. and Soviets. 
 
As an aside, the last sentence is HIGHLY unlikely.  Genetic Engineering might not be that difficult to someone who knows what they are doing, but nothing ever works on the first try and someone who is not well practiced at it will have a bitch of a time.  I also highly doubt that anyones "mom" has a $10,000 pcr machine in their basement, or any live genetic material of a select agent.  To say that crap is regulated is a gross understatement. 
 
Oh, and conferring antibiotic resistance is also not hard.  Just because something isnt in the literature most certainly does NOT mean is hasnt happened.  You think Uncle Sam or Mr. Russia published all their hard one biological weapons data?  If you do, I have some ocean front property to sell you in Missouri.  Some highly exotic shit is out there, and there is potential for some REALLY crazy stuff too.  Drug Resistant Plague would hardly be unusual compared to what their could be...
 
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Paul_In_Houston       8/6/2009 11:20:12 AM
I also highly doubt that anyones "mom" has a $10,000 pcr machine in their basement, or any live genetic material of a select agent.  To say that crap is regulated is a gross understatement. 
 
I suspect that the author was making the point that such a superbug would most likely be released under the most improbable chain of circumstances.
 
When I first saw "Dr. Strangelove", in my twenties, my tender young mind rebelled at the chain of coincidences necessary for that scenario to happen.  I had yet to become fully acquainted with "Murphy's Law" (the GOD of my later engineering and IT careers), and didn't realize that was EXACTLY how such a thing could happen.
 
You see, the better we get at anticipating problems, and preventing them, the more improbable the chain of events that have to occur before disaster strikes.  It's like the sieve of evolution;  we actually get fewer disasters in the long run, but the ones that DO happen are more and more improbable.  Chernobyl and Three-Mile Island come to mind.
 
So, COULD some teenage dip bring about a new version of "The Stand"?
 
Maybe a bit more likely than than the bug escaping from some super secret laboratory, for the reasons I outlined above.
 
Cheers!  :-)

 
 
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RtWingCon    points valid but,,,   8/7/2009 2:21:14 AM
Previous points sound valid and i agree, but it appears a pandemic is trying to take hold from multiple sources. Pneumonic Plaque only being the latest. It appears the Swine Flu is gaining steam, remember how bad Ebola was, how about the Hanta Virus, Bird Flu, SARS etc, etc. Judging from the past 10yrs, disaster will likely come naturally. As the previous posts pointed out, a "special" made bug is indiscriminate. Only a retarded nation like N.Korea or Iran(retarded leaders) and such would unleash home brews. It's doubtful they have the resources to develop them. On second thought, that's exactly what Saddam was trying to do. Oh well, pray for the best.
 
 
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fixerdave    Not hard at all...   8/7/2009 4:17:58 PM
Nature makes superbugs and pandemic strains of viruses all the time, just need a few pigs, chickens, and people in close proximity - add a little time...  You don't really need genetic engineering with viruses, they do the recombination thing all by themselves.  It probably wouldn't be that hard to deliberately create the next pandemic.
 
The issue for deliberate weaponisation is survivabililty, not lethality.  That's the problem, for most people.  Now, let's make some wild assumption that there are people out there that are willing to die in the process... not a big stretch.  Now, let's make some wild assumption that there are people out there that want to kill everyone, not just a particular ethnic/political group, but EVERYONE... not that big of stretch either.  Some people hear voices in their heads... "And there will be destruction of the Earth, and YOU shall be the agent of this destruction..." that kind of crap. Or, someone may come to realise that the only way to save the animals is to kill all the people.  Whatever.  Sooner or later, one of these nut-jobs will also have the ability to create and spread some kind of nasty.  It will happen.
 
The question is: will we be ready?   I expect that all this pandemic hype is just an exercise in getting ready.  If not deliberately so, it will have the same effect anyway.  So, hurray for swine flu, bird flu, whatever.
 
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FJV       8/7/2009 4:25:56 PM
Why do I suspect that genetic modification will be several orders of magnitude harder to do than making a simple pipe bomb?
 
 
 
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Wicked Chinchilla       8/7/2009 11:46:03 PM

Why do I suspect that genetic modification will be several orders of magnitude harder to do than making a simple pipe bomb?


 
 That in itself is a gross understatement.  I have done genetic modifications.  As I have said: its a bitch.  Your technique must be perfect.  Your materials must be perfect.  There is so much that can go wrong counting only stuff we absolutely know without going into the random happenstance that biology tends to throw in there.  It is most assuredly NOT easy, and NOT something some lay person is going to do at home in a basement.  Could an expert do it in a basement?  Probably, but they would need top of the line equipment and material to do so.  
In terms of other viruses popping up, nothing as yet is as deadly as one of the Zaire strains of Ebola.  We are talking mortality of 90% here.  Other variants of Ebola range from 70 - 20.  Marburg virus is a close cousin and hovers around 40% mortality generally.  Flu in comparison is 0.2%.  What makes pandemic flu scary is 1) the ability to pick up more deadly attributes from more virulent flu's 2)  It spreads SOO damn easily you get hundreds of millions if not billions infected.  At 0.2% thats still a boatload of people dead.  I would no worry about Ebola or Marburg being a planet killer because they kill so fast.  The outbreaks burn themselves and the available population out.  Its also an extremely...public disease.  People tend to avoid those dripping and oozing, blood, bile, and all sorts of assorted fluids out of every oriface.  Hemorragic Fevers are very, very nasty.   Hanta virus isnt that bad and actually is not human - human transmissable.  Its mrtality I think hovers around 10% if memory serves and is spread mostly through dried inhaled rodent feces.  

Sars...was handled.  It was panic mode for a bit there because the Chinese acted like complete fucking idiots and didnt notify anyone of the disease until hundreds were dead already.  We are extremely lucky we took it as seriously as we did but the media coverage was still over blown. 
 
However, despite all that a major global threat is far, far more likely to be naturally made instead of man-made.  This is because engineering a killing virus like that would take money, equipment, and expertise that is 1) not common and 2) extremely expensive.  Everyone KNOWS who has the knowledge and the materials necessary.  Plus, biological weapons that would spread around the world would kill your own nation-state.  Due to the scarcity and expense of the knowledge and resources necessary only nation-states could truly expect to succeed.  Its contradictory to pursue such a virus when something like Anthrax is very effective, relatively cheap, and cannot be spread human to human.  
 


 
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